Endoscopic gastritis is a term used when there is an inflammatory change in the gastric mucosa like color and/or structure that was noticed by endoscope. Is to assesses the effect of these factors and association of adiponectin with these factors. This is a case-controlled study. The study consists from 100 subjects. Eighty of them had gastritis by endoscopy Forty of them were H. pylori positive and the rest were H. pylori negative. The rest twenty persons were healthy control group. Demographic information’s were taken like age, sex and others by questionnaire. Endoscopy and lipid profile were done for them. Adiponectin was significantly lower ( P=0.001) in gastritis patients whether infected (8.783±0.968) with H pylori or not (8.278 ±0.838) when compared with control group (9.119±0.1593) (Table-1-). Regarding lipid profile , there was a significant in all parameters of lipid profile in gastritis patients than healthy group (Table-1-). Analysis of correlation between adiponectin and BMI and weight demonstrated a negative correlation with gastritis with h pylori infection (r= -0.068 and r=0.356 respectively). This study shows that adiponectin had an important role in gastritis especially when there is an h pylori infection. Its level had a negative correlation with BMI and lipid profile.