0973-7510 Journal of Pure and Applied Microbiology 2581-690X DR. M.N. Khan 10.22207/JPAM.12.3.20 A Bacterial Profile of Scrub typhus Infections in North Karnataka and their Isolation by Serological and Molecular Method Shahid S. Mohammed B. Sirwar Siddesh Vijayaraghavan R Department of Microbiology, Khaja Bandanawaz institute of Medical Sciences, Gulbarga and PhD scholar, Saveetha University, Chennai - 602 105, India. Department of Microbiology, Khaja Bandanawaz institute of Medical Sciences, Gulbarga - 585 104, India. Director of Research, Saveetha Medical University, Thandalam, Chennai - 602 105, India. 30 09 2018 12 3 1201 1204 Copyright © 2018 The Author(s) 2018 This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.https://creativecommons.org/licenses/by/4.0/

Scrub typhus infections are caused by Orientia tsutsugamushi and similar to febrile infections which makes more difficult in diagnosis. Present study revealed the incidence of scrub typhus infections. A total 521 samples which are Weil-Felix positive were selected in the present study and analysed by PCR over a period of one year in Khaja Banda Nawaz Institute of Medical Sciences, Gulbarga. The incidence rate was 29.36 % (153/521) of cases were positive and 39.06 % (84/215) of cases were males and 22.54 % (69/306) of cases were females. More than 30 years of age group population had highest incidence rate. Species specific gene 56 kDa was selected for the confirmation of scrub typhus. Multiple clinical features was observed along with rash and eschar. Early diagnosis help to reduce the morbidity and mortality.

Keywords Scrub typhus eschar Weil- Felix test RT-PCR