A urinary tract infection (UTIs) is the one of the most common bacterial infection in women than in men, at a ratio of 8:1 and a major cause of morbidity. Approximately 50–60% of women report at least one UTI in their lifetime. UTI is caused by pathogenic invasion of the urinary tract which leads to an inflammatory response of the urothelium. The clinical manifestation of UTI depend upon the portion of the urinary tract involved, the etiologic organism, the severity of the infection and patients ability to mount an immune responds to it. Signs and symptoms include fever, dysuria, and urinary urgency, cloudy or malodorous urine. UTI is higher in women due to several clinical factors including anatomic differences, hormonal effects and behavioral pattern. Malnutrition, poor hygiene, low socioeconomic status is associated with UTI and these factors are rife in rural settings. UTI is mostly caused by gram negative aerobic bacilli found in GI tract. Included in this family are the Escherichia coli (E. coli), Klebsilla, Enterobactor, Citrobacter, Proteus and serratia species. Other common pathogens include Staphylococcus epidermidis, Staphylococcus saprophyticus and Enterococcus Species. E. coli is the most predominant organism. The aim of this review is to summarize the distribution, clinical sign and symptoms, laboratory profile and risk factor of urinary tract infection.