Most urban rivers are polluted due to the indiscriminate human and industrial activities. As more rural people migrate to urban cities for a greener livelihood, it is expected that river pollution would continue to be one of the core issues regarding attention by governments and all civil society organisations in many African countries. Apart from the public health dangers of river pollution, aquatic life e.g. fish is heavily affected also. Bacterial technology has been implemented in parts of China for river quality remediation. The paper explores the possibility of adopting such a technology in Africa. The paper also presents concept notes on how the use of such a technology can be integrated to the mainstream sustainable water resources management scheme in Africa. The paper anticipates contributing in part towards government and civil society organisations’ effort towards safe health, hunger eradication and poverty alleviation in Africa.