Four fluorinated triphenylphosphine (PPh₃)-based organic salts were synthesised from PPh₃ and á,á’–dibromo-p-xylene by first producing quaternised salts, followed by anionic exchange with fluorinated anions, NaBF₄, KPF₆, CF₃SO₃Li and CF₃COONa.  This is the first reported synthesis of the trifluoromethyl sulphonate and the trifluoro acetate ionic salts with the 1,4-phenylenebis(methylene)bis(triphenylphosphonium) dication.  The compounds were synthesised in yields of between 80-98% using simple techniques. The salts were characterized by ¹H, ¹³C, ¹⁹F and ³¹P NMR, and IR spectroscopy. The organic salts showed significant activity against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Candida albicans, and Streptococcus pyogenes when compared with the activities of the standard antimicrobial chloramphenicol and antifungal nystatin.