ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Rajendran Venkatasubramani1 and Thirumoorthy Viswanathan2
1Research and Development Centre, Bharathiar University, Coimbatore – 641 046, Tamilnadu, India.
2Department of Microbiology, LRG Government Arts College for Women, Tirupur – 641 604, Tamilnadu, India.
J Pure Appl Microbiol, 2019, 13 (3): 1803-1813 | Article Number: 5719
https://doi.org/10.22207/JPAM.13.3.57 | © The Author(s). 2019
Received: 16/07/2019 | Accepted: 02/09/2019 | Published: 16/09/2019
Abstract

Opportunistic pathogens prevail in the hospital environment, and utensils are the root cause of severe nosocomial infection. These pathogens exhibit high antibiotic resistance due to constant exposure to drug therapy. This study focuses on screening antibiotic-resistant opportunistic pathogen and effectiveness of piperidine compounds against the opportunistic pathogens. Standard microbiological laboratory protocols were used and followed, and about 238 samples were processed and screened. Among them, 47 reported positive for the presence of pathogens like Staphylococcus species, Salmonella species, Pseudomonas species, Proteus species, E. coli and Klebsiella species. In antibiotic resistance screening, the maximum resistance percentage was recorded against Ampicillin and Chloramphenicol (100%). The least percentage of resistance was noticed against Carbenicillin (41%). Piperidine compounds showed promising susceptibility towards test isolates. The MIC of the compounds against E. coli and Staphylococcus sp. was found to be higher when compared to Klebsiella sp.

Keywords

opportunistic pathogens, piperidines, antibiotic resistance, nosocomial infection.

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© The Author(s) 2019. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.