ISSN: 0973-7510

E-ISSN: 2581-690X

M.S. Shree Devi1 , V. Ravichandiran2 and S. Jeyakumari3
1Reader, Sivaraj Siddha Medical College, Salem, Tamilnadu, India.
2Director, School of Pharmaceutical Sciences, Vels University, Chennai, India.
3Prof. Department of Pharmacognosy, Vels University, Chennai, India.
J. Pure Appl. Microbiol. 2014, 8(6):4897-4902
© The Author(s). 2014
Received: 11/07/2014 | Accepted: 23/10/2014 | Published: 31/12/2014
Abstract

The study deals with antibacterial and antifungal activity of selected single plants (Adathoda vasica, Ocimum tenuiflorum, Solanum xanthcarpum, Tylophora asthmatica) and its Siddha formulation. The antibacterial and antifungal activity was determined using the hole-in-plate bio assay procedure. Staphylococcus aureus, Escherichia Coli, Pseudomonous arrigonosa, Bacillus subtilis (antibacterial) Candida albicans and Aspergillus niger (antifungal) were used as the test microorganisms. In this microbial study the findings shows Siddha formulation are having more antibacterial activity than antifungal activity which is determined by zone of inhibition, MIC and MBC on different bacterial and fungal strains. Further, the results of antibacterial activity of siddha formulation were compared with standard drug Amoxcillin and for anti fungal activity of siddha formulation were compared with standard drug chloramphenicol.

Keywords

Siddha formulation, Antimicrobial activity, Antifungal activity, Hole-in-plate bio assay

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