The present study was carried out to detect the association of miR-146a haplotypes polymorphisms with Behcet’s Disease in Iraqi patients, PCR-SSCP technique used in present study, blood was used to DNA extraction, the results show that there was strong association between miR-146a and Behçet’s Disease there were two patterns (A and B), polymorphisms show significant differences (p>0.05) between patients and control where haplotype A was appeared in control with (4% ) while in patients (43%) and haplotype B was appeared in control with (96% ) while in patients (57%). The present study concluded that there was association between miR-146a polymorphisms with Behçet’s Disease, our finding need more investigation to use this polymorphism as early indication of Behçet’s Disease incidence.
miR-146a, PCR-SSCP technique, Haplotypes, Polymorphisms
© The Author(s) 2018. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.