ISSN: 0973-7510

E-ISSN: 2581-690X

Lu-lu Li, Qiang Zhang2 , Jin Tan2 and Yun-yun Fang1
1Tianjin Medical University, Tianjin, China.
2Institute of Geriatrics, Tianjin Medical University General Hospital, Tianjin, China.
J Pure Appl Microbiol. 2013;7(Spl. Edn.: April):195-199
© The Author(s). 2013
Received: 03/03/2013 | Accepted: 14/04/2013 | Published: 30/04/2013
Abstract

Obstructive sleep apnea (OSA) is characterized by repetitive upper airway closures or partial collapses that occur during sleep. Evidence from well-defined studies has shown that OSA is associated with increased incidence of diabetes. In this article, we will review the current evidence that links OSA to glucose metabolism disorders, discuss the potential mechanisms by which OSA may contribute to the development of glucose metabolism disorders, and summarize briefly the studies on the impact of treatment of OSA on glucose metabolism.

Keywords

Obstructive Sleep Apnea, glucose metabolism disorders, type 2 diabetics, CPAP, sympathetic nervous system activity, sleep fragmentation, oxidative stress,
Inflammatory mediators

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© The Author(s) 2013. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.