ISSN: 0973-7510

E-ISSN: 2581-690X

Yongze Yu, Yuanyuan Liu , Shuhui Fang and Qingxi Hu
1Rapid Menufacture Engineering Center, Shanghai University, Shanghai, China.
J Pure Appl Microbiol. 2013;7(Spl. Edn.: April):209-213
© The Author(s). 2013
Received: 03/03/2013 | Accepted: 14/04/2013 | Published: 30/04/2013
Abstract

Solvent evaporation is one of critical factors to influence the microstructure characteristics and organic solvent residual in electrospinning scaffolds. Here, according to the Double-Film Theory and the Law of Mass Conservation,we present a nonlinear mass diffusion-transfer model of the polymer jet in electrospinning to describe the solidification process of fibers.With polycaprolactone / dichloromethane (PCL / DCM) for example, we use the model to predict transient radius changes and solvent concentrationprofiles. Numerical simulation results demonstrate that the degree of high transient inhomogeneity for solvent concentrationin jet cross-section decreases with the radius decreased. The fiber curing time reduces with the radius of jet reducing. The results indicate that we need to couple multiphysics models to improve and optimize the solvent volatilization model.

Keywords

Mathematical model, Electrospinning, PCL, tissue engineering

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