Tuberculosis (TB) is presently recognized as one of the most common opportunistic infections seen in HIV seropositive patients, mostly presenting in the form of pulmonary and extrapulmonary infections. A total of 100 clinically diagnosed and radiologically evident cases suggestive of pulmonary tuberculosis were selected for study. Sputum sample of each patient was screened for Acid Fast Bacillus (AFB) by Ziehl Neelsen staining and cultured. On examination 70 smears were found positive for AFB and 30 smears were negative by concentration method. A total of 27 samples were found to be culture positive and 73 were culture negative, of these 26 stains were identified as Mycobacterium tuberculosis, one was identified as M.avium complex (MAC). Of the 100 patients 15 were seropositive for HIV-I antibodies. Out of 15 seropositive patients, 2 patients smear and culture were positive and identified as M.tuberculosis, one patient shown culture positive and smear negative and the other patients culture and smear were both negative for AFB.