ISSN: 0973-7510

E-ISSN: 2581-690X

Xiao-Yang Zhao1, Jing Zhang1, Xiu-Dong Chen2, Shan-Qiang Wang2, Ya-Meng Yang2, Ya-Xing Jing1 and Zhen-Yu Zheng1,2
1College of Life Sciences, Henan Agricultural University, Zhengzhou – 450 002, PR China.
2College of Animal Science and Veterinary, Henan Agricultural University, Zhengzhou – 450 002, PR China.
J Pure Appl Microbiol. 2013;7(Spl. Edn.: November):565-575
© The Author(s). 2013
Received: 27/09/2013 | Accepted: 04/11/2013 | Published: 30/11/2013
Abstract

In this study, Illumina sequencing was used for transcriptome analysis of subcutaneous adipose and intramuscular adipose from exotic breeds (Landrace pigs) and domestic breeds (Taihu pig). For each library,1961 differentially expressed (DE) genes of the subcutaneous adipose between Landrace and Taihu pigs were identified. Fifty-four DE genes had functions described in the GO database and 15 DE genes were involved in the PPAR signaling pathway and fatty acid metabolism pathway described in the KEGG pathways. Comparison of intramuscular adipose between Landrace and Taihu pigs revealed 1219 DE genes. Fifty-five DE genes had functions described in the GO database and 12 DE genes were involved in the PPAR signaling pathway and fatty acid metabolism pathway. Digital analysis expression by tag profiling was a powerful approach to comprehensive transcriptome analysis to identify changes associated with fatty deposition, leading to a better understanding of the underlying mechanism of pathogenesis of fatty deposition.

Keywords

Subcutaneous adipose, Intramuscular adipose, Differentially expressed gene, Pig

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