ISSN: 0973-7510

E-ISSN: 2581-690X

Mina Saadat1 and S.R. Mohammadi2
1Department of Basic Science, Azad University, Research and Science Branch, Tehran, Iran.
2Department of Medical Mycology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
J Pure Appl Microbiol. 2014;8(1):301-305
© The Author(s). 2014
Received: 20/06/2013 | Accepted: 12/09/2013 | Published: 28/02/2014
Abstract

Bacterial biofilms are complex organized communities of bacteria that surrounded by exo-polysaccharide and grow in association with surfaces. They are thought be responsible for 65% of nosocomial infection and can be found at almost solid-liquid interface including medical implant and catheters. One of the most medically important biofilm forming species is Pseudomonas aeroginusa Because of increasing antibiotic resistant, it is necessary to find suitable agent to limit contamination of surfaces and medical devices. In this study Titanium Dioxide (TiO2) nanoparticles was synthesized from Titanium tetrachloride (TiCl4) through sol-gel method. Properties of synthesized nanoparticles were evaluated by X-ray diffraction and scanning electron microscopy methods. Catheter and glass chips were coated with TiO2 nanoparticles. Based on XTT results and scanning electron microscopy data it was showed that pseudomonas aeroginusa biofilm formation has effectively decreased on TiO2 nanoparticles coated catheter and glass chips compared to control group.

Keywords

TiO2 nanoparticles, P. aeruginosa, Biofilm formation, Coated surfaces

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