J Pure Appl Microbiol | Research Article | Volume 12, Issue 4 | Article Number: 5279

Khalil Ismail A. Mohamed1*, Wifaq M. Ali Al-Wattar1, Ghada Ibrahim Taha2, Saad Hasan Mohammed Ali 1, Huda Q. Mohammed Abu-Al-Ess1, Suha A. Al-Fukhar1 and Jinan M. Mousa1

1Clinical Communicable Diseases Research, College of Medicine, University of Baghdad, Baghdad, Iraq. 2Department of Basic Sciences, College of Dentistry, University of Baghdad, Baghdad, Iraq.

Corresponding Author E-mail: dr.alkarkhi@gmail.com
Received: 09/09/2018| Accepted: 20/10/2018 |Published: 28/12/2018
DOI: http://dx.doi.org/10.22207/JPAM.12.4.37

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Abstract

The study was carried out during a period of February 2017-July 2018 for the detection of brucellosis in 128 suspected patients with age group range from 17 – 69 years, who attended to Baghdad teaching hospitals, that had been examined and defined as suspected cases by specialized physician with the recording of clinical manifestation. The diagnosis done by Rose Bengal test (RBT) method, a blood sample was taken from each patients as well as other 30 healthy control matching in age and gender. The study included measurement of the concentration of Interleukin-23, activity of Acidphosphatase, Copper and Zinc in sera of patients and healthy control. The result indicated that Rose Bengal test positive in 18 cases, 12 with a titer of 1:160 and 6 cases with a titer of 1:320. The Level of IL-23, Acid phosphatase increased significantly, with no statistical difference in copper and zinc concentration in both interval ages of patients sera in comparison with healthy control.

Keywords: Brucellosis, Interleukin-23, Acidphosphatase, Copper, Zinc.