ISSN: 0973-7510

E-ISSN: 2581-690X

M.P. Saraswathy1, Santhosh B. Patil1, Baskaran1, U.M. Dhanalekshmi2 and H. Shankar Narayana1
1Department of Microbiology, Melmaruvathur Adhiparasakthi Institute of Medical Sciences & Research, Melmaruvathur – 603 319, India.
2Bio Organic Lab, CLRI, Adyar, Chennai – 60 020, India.
J Pure Appl Microbiol. 2013;7(2):1427-1430
© The Author(s). 2013
Received: 03/11/2012 | Accepted: 04/12/2012 | Published: 30/06/2013
Abstract

HCV and HBV are most problematic infections in haemodialysis patients.
The cause and source of infection is multiple in haemodialysis patients. Blood transfusion, contaminated equipment and patient to patient transmission are the potential source of infection. Our aim is to find out the prevalence of these infections in our haemodialysis centre.  This study was carried out between June to November 2011. A total of 60 end stage renal disease (ESRD) patients who are on dialysis and 15 technical staff were enrolled in cross sectional study to determine prevalence, risk factor and consequences of HCV infection. Serum samples were tested for anti-HCV and HBsAg by immunochromatography test. Subsequently anti HCV positive samples were analysed with third generation anti HCV test-ECLIA.  Prevalence of anti-HCV was 8.3% and HBsAg was 1.66%. Both the tests were negative in staff. The HCV infection has correlation with male gender, long term HD and units of blood transfusion. Overt liver disease rarely occurs in patients with ESRD. In our study, Chronic liver disease with elevated liver enzymes, were detected in 40% of HCV patients. The prevalence of HCV and HBV infections are low in our setup. It requires stringent adherence to all universal precautions to decrease the infection rate.

Keywords

Haemodialysis, HCV, HBV, Infections, Patients, Immunochromatography

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