ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Ali A. Mohy , Ahmed Abdul jabbar Jaloob Aljanaby and Saleem Khteer Al-Hadraawy
Department of Biology, Faculty of Science, University of Kufa, Iraq.
J Pure Appl Microbiol, 2019, 13 (3): 1737-1743 | Article Number: 5727
https://doi.org/10.22207/JPAM.13.3.48 | © The Author(s). 2019
Received: 20/07/2019 | Accepted: 03/09/2019 | Published: 19/09/2019
Abstract

The current study is trying to identify some effects of scabies on some vital indicators such as (ECP, IgE, MCP-1 and IL-17). The results showed that levels of ECP has significant increase (P<0.05 (9569.3 ±256.10 pg /ml), (9872.9± 260.50) respectively in comparison with the control group (7665.2 ± 385.72 pg /ml), (7834.1± 251.43 pg /ml) respectively, The result proved that there was the significant increase (P (9721.1 ±181.15 pg /ml), (7749.7± 226.75) respectively in concentration of (ECP) in patients with S. scabiei and total healthy individuals. The levels of IgE had significant increase (P (284.8 ±34.05 IU /ml), (249.85± 13.682 IU /ml) respectively in comparison with the control group (119.5 ± 11.24 IU /ml), (108.77± 8.3 IU /ml) respectively. The result indicate that there was significant increase (P (267.134 ±18. 334 IU /ml), (114.13± 6.94 IU /ml) respectively in concentration of (IgE) in total patients infected with S. scabiei and total control group. The levels of MCP-1 has significant increase (P (271.76 ±29. 88 pg /ml), (246.983± 27.57 pg /ml) respectively in comparison with the control group (153. 27 ± 21.071pg/ml), (154.67± 22.973 pg /ml) respectively, Also it revealed the significant increase (P (259.29±20. 22 pg /ml), (153. 97± 15.21 pg /ml) respectively in concentration of (MCP-1) in S. scabiei patients and total healthy individuals. IL-17 had significant increase (P (16.318 ±0. 71 pg /ml), (16.847± 0.58 pg /ml) respectively in comparison with the control group (5. 6009 ±0. 45 pg/ml), (5.2023± 0. 35 pg /ml) respectively. The current study shows that there was significant increase (P (16.583±0. 45pg /ml), (16.4016± 0.28 pg /ml) respectively in concentration of (IL-17) in total patients infected with S. scabiei and total healthy individuals. The levels of IL-2 had significant increase (P (21.14 ±0. 8081 pg /ml), (21.800± 1.0644 pg /ml) respectively in comparison with total healthy individuals (7. 447 ±0. 2422 pg/ml), (7.7235± 0. 1716 pg /ml) respectively, Also it revealed the significant increase (P (20.972±0. 6626pg /ml), (7.5853± 0.1480 pg /ml) respectively in concentration of (IL-2) in total patients infected with S. scabiei and total control group. Conclusions: the results indicate that infection of scabies influences on the human immunity represented by the ECP, IgE MCP-1 and IL-17 in patients infected with scabies and may be used as good biomarkers in detection of scabies.

Keywords

scabies, Eosinophilia, Cationic protein, IgE, IL-17, MCP-1.

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© The Author(s) 2019. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.