ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access

Natesan Gopal1 , Jane Ekegbu2, Christina Parvinder Kaur2, Ponnaiah Paulraj2,Raji P.3 and Karanam Sai Bhavya3

1Faculty of Pharmacy, MAHSA University, Jalan SP 2, Bandar Saujana Putra, 42610 Jenjarum Selangor, Malaysia.
2Department of Biomedical Sciences, Faculty of Medicine, MAHSA University, Jalan SP 2, Bandar Saujana Putra,42610 Jenjarum Selangor, Malaysia.
3Department of Biotechnology, Sathyabama Institute of Science and Technology, JeppiaarNagar, Rajiv Gandhi Salai, Chennai – 600 119, India.
J Pure Appl Microbiol, 2019, 13 (2): 957-965 | Article Number: 5584

https://dx.doi.org/10.22207/JPAM.13.2.32 | © The Author(s). 2019 

Received: 18/03/2019| Accepted: 01/05/2019 | Published: 11/06/2019
Abstract

The number of multi-drug resistant microbial strains and the appearance of strains with reduced susceptibility to antibiotics are continuously increasing and it has been attributed to indiscriminate use of broad spectrum antibiotics. It is common sense that the scarcely explored extensive Malaysian biodiversity would yield countless opportunities to find plant species potentially secreting metabolites, exhibiting antimicrobial activity, among other medicinal properties. In this study leaves and barks of Rhizophora stylosa were collected and extracted using various organic solvents such as petroleum ether, chloroform and methanol. These crude extracts were further evaluated for antimicrobial properties by different methods against Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aueroginosa. The bark extracts were more potent than leaf extracts of R. stylosa. The chloroform extracts were found to have the highest antimicrobial activity with an MIC of 0.1 mg/ml and MBC of 6.3 mg/ml.

Keywords

Leaves, Bark, antimicrobial properties.

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© The Author(s) 2019. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.