Agricultural  wastes are low cost, renewable and most abundant raw materials  present in environment. Different agricultural wastes were tested for xylanase production  from Saccharomyces cerevisiae. Mixed culture of soy bean and wheat bran  (4:6) was most effective against pathogenic fungi and suitable for maximum xylanase production  at pH 5.0 after 48 h incubation period. Xylanase  was  stable at 55°C for 20 min. The molecular weight of crude xylanase was 74 KDa. Coating of citrus fruits with S.cerevisiae grown on mixture of wheat bran and soybean was highly significant reduction of both disease incidence and disease severity. Xylanase can be used as biocontrol for green and blue mold of orange and lime fruit.