Determining Total Phenolic Content of Paeonia sinjiangensis K.Y. Pan and its Antimicrobial Activity Grown in Xinjiang, China

ISSN: 0973-7510

E-ISSN: 2581-690X

Determining Total Phenolic Content of Paeonia sinjiangensis K.Y. Pan and its Antimicrobial Activity Grown in Xinjiang, China

Haiyan Gong¹, Lanying Hu¹, Chen Zhang¹, Ming Zhu², Bin He¹, Qingling Geng¹, Bo Zhang³ and Xuehan Wang¹

¹The Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi – 830 000, Xinjiang, China.

²Xinjiang Medical University, Urumqi – 830 000, Xinjiang, China.

³The First People’s Hospital of Wenling City, Wenling – 317 500, Zhejiang, China.

J Pure Appl Microbiol. 2013;7(1):365-369

Received: 08/01/2013 | Accepted: 04/03/2013 | Published: 31/03/2013

Abstract

Paeonia sinjiangensis K. Y. Pan is a perennial herb belonging to the family Ranunculaceae which is one of the most important crude drugs in traditional Chinese medicine, used as an anti-inflammatory, analgesic and sedative agent. This paper deals with the detailed total phenolic content of the crude drug Paeonia sinjiangensis K.Y. Pan, from Xinjiang, China. Meanwhile, it tested for antimicrobial activity in this study. The total phenolic content of Paeonia sinjiangensis K.Y. Pan was 9.58 ± 1.03 mg QE/g dry wt. The microscopic characteristics were investigated, which offer data to differentiate the drug from its other species. It showed strong inhibition against Blastomyces albicans and possessed considerable activity against Staphylococcus aureus and Escherichia coli.

Keywords

Antimicrobial activity, Paeonia sinjiangensis K.Y. Pan, phenolics

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