Dengue is a major health problem in many parts of the tropical world presenting as both epidemic & endemic forms. It is a mosquito borne illness caused by one of the serotypes of dengue viruses. Mortality rate of dengue in untreated patients is 10%-12%. The present study aims to determine whether the rapid test SD dengue duo (IgG, IgM, and NS-1 Ag detection) can be used as screening test in dengue outbreak when compared to ELISA. 226 serum samples were tested in patients clinically suspected Dengue. All the 226 samples were subjected to IgG, IgM Microlisa test. The same were put on rapid SD bioline Dengue duo rapid test and was compared with ELISA. 150 samples were tested positive with ELISA (either positive for IgG, IgM). When compared with ELISA, Rapid test showed sensitivity of 80.6% specificity and positive predictive value of 100% & zero false positive rates. Efficiency of the test was 87.16% SD Dengue duo rapid test should be a valuable screening test for dengue fever outbreak which can be interpreted easily. Results were comparable to ELISA. It provides additional diagnostic investigation of primary and secondary dengue that compliments NS-1 antigen detection.