ISSN: 0973-7510

E-ISSN: 2581-690X

S. Deepa1 and Shobha D. Nadagir2
1Department of Microbiology, Mysore Medical College and Research Institute, Mysore – 570 001, India.
2Department of Microbiology, KIMS, Hubli, India.
J Pure Appl Microbiol. 2012;6(3):1203-1207
© The Author(s). 2012
Received: 15/01/2012 | Accepted: 03/03/2012 | Published: 30/09/2012
Abstract

Community acquired methicillin resistant Staphylococcus aureus (CA-MRSA) is an emerging pathogen. There is considerable concern that CA-MRSA may cause infections difficult to treat in the outpatient settings. The present study was undertaken to know the incidence of CA-MRSA and  its antibiotic sensitivity pattern. A total of 214 methicillin resistant Staphylococcus aureus were detected using oxacillin disk diffusion method. Clindamycin sensitivity was used as surrogate marker for screening CA-MRSA. Clindamycin sensitive MRSA with no obvious history of hospital acquired infection were analyzed further genotypically for molecular characterization. Clindamycin sensitive MRSA were 122(57%). Among these  109 isolates were presumed to be CA-MRSA. Of these 83(76.14%) were positive for mecA gene. Forty four (53%) revealed SCCmec type III, 34(40.96%) were SCCmec type III A and  4(4.81%) had SCCmec type IV cassettes. Nineteen  isolates showed pvl gene. Only 4(4.81%) of clindamycin sensitive MRSA were genotypically proved as CA-MRSA. CA-MRSA were susceptible to erythromycin, gentamicin, ciprofloxacin, co-trimoxazole, tetracycline and vancomycin. There is a need for judicious selection of antimicrobial agents and effective infection control programmes  to prevent the spread of community acquired infections.

Keywords

Staphylococci, methicillin resistance, CA-MRSA

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© The Author(s) 2012. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.