J Pure Appl Microbiol | Review Article | Volume 13, Issue 1 | Article Number: 5260

Jureka Mankotia1, Sunil Sethi2 and Mohammad Azhar Khan1*

1Department of Biotechnology, Shoolini University, Bhajol, Solan – 173 239, HP, India. 2MD Microbiology, PGIMER, Chandigarh, India.

Corresponding Author E-mail: mk.azhar1@gmail.com
Received: 15/07/2018| Accepted: 03/09/2018 |Published: 19/02/2019
DOI: http://dx.doi.org/10.22207/JPAM.13.1.18

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ABSTRACT

Emergence of Tuberculosis and Multi drug resistance tuberculosis at higher pace in the population needs rapid diagnosis with accuracy to reduce the transmission of disease and suffering of the patients. The technique of GenexpertMTb/Rif by Cepheid rolled out by WHO has given high support to the humanity by rapid and accurate detection of Tuberculosis and resistance to rifampicin. The technique has less turnaround time, can be performed in simple lab settings, fully automated processing and result interpretation and the professional needs a hands on training of less than thirty minutes as compared to other sophisticated techniques for TB and drug resistance diagnosis. The article here discussed the role of CBNAAT in different groups of patients with accordance to the researches already published in support of high and promising performance of GenexpertMTb.

KEYWORDS 

GenexpertMTb, CBNAAT, Tuberculosis, Diagnosis, Rifampicin, Resistance.

Citation: Jureka Mankotia, Sunil Sethi and Mohammad Azhar Khan, Cartridge Based Nucleic Acid Amplification Test: The Sherlock of Tuberculosis, J Pure Appl Microbiol., 2019; 13(1):179-182 doi: 10.22207/JPAM.13.1.18

 


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