The aim of this paper was cadmium removal from waste water using SiO₂ nanoparticles and fungal biomasses. Five treatments were used for cadmium removal. They were inactivated mycelia of Cladosporium sphaerospermum (CLA) and Fusarium oxysporum (FUS), SiO₂ nanoparticles (N-Si) and their combinations (N-Si-CLA and N-Si-FUS). The biosorbents natures and combinations were examined by Fourier Transform Infrared (FT-IR) and Scanning Electron Microscope (SEM) where close attachments between combined biosorbents were detected. Different factors affecting cadmium biosorption capacity were tested. It was found that (N-Si-CLA) and (N-Si-FUS) were the most potent biosorbents at pH 7. Thirty minutes contact time exerted maximum sorption capacity. Initial cadmium concentration was optimum at 0.5 mol^-1 for highest biosorption capacity. Ca²⁺ displayed synergistic interfering more than Na⁺ and K⁺, respectively. Two real waste water samples collected from two factories were tested to depollute cadmium using the five sorbents. (N-Si-CLA) and (N-Si-FUS) were the most potent adsorbents, where 65.73 % and 54.30% removed in the first sample and 61.33 % and 56.50 % in the second one, respectively. From the results, it was concluded that bioremediation of cadmium from waste water was possible by using SiO₂ nanoparticles and fungal biomasses with high efficiency of their combinations.