Journal of Pure and Applied MicrobiologyVol. 1 No. 2

Antimicrobial Studies of Metal Complexes of Fe(III), Co(II) and Ni(II) with Cyanex-272

T. Pal1, M.S. Zoha2*, B. Roy2, B.C. Sarker2, M.A. Hakim², A.A.A.A. Islamı and A. Alamı

1Department of Chemistry, Rajshahi University of Engineering and Technology, Rajshahi, Bangladesh. 2Department of Agricultural Chemistry and Biochemistry, Hajee Mohammad Danesh Science and Technology University, Dinajpur-5200, Bangladesh.

Received on 22 August 2007 and accepted on 29 September 2007

 

ABSTRACT

Metal cheletes of Fe(III), Co(II) and Ni(II) with bis(2,4,4-trimethyl pentyl)phosphinic acid (cyanex-272; abbreviated as LH) were synthesized. The prepared complexes have the compositions: 1. [Fe(L)3], 2. K[Co(L)3] and 3. [Ni(L)2]. Their conventional physical and chemical analysis had been done. Their anti-bacterial and antifungal activity had been evaluated. Disc diffusion methods were employed for antimicrobial assays against four human pathogenic bacteria and fungi. The biological properties of the metal complexes reveal that the complex 3 is more effective against almost all antibacteria tested. Furthermore, the complexes 1 and 3 show the height antifungal activity against the fungi Trichophyton sp. and Aspergillus flavus.

Keywords : Antibacterial activity, antifungal activity, cyanex-272.