Journal of Pure and Applied MicrobiologyVol. 9 No. 3

Histopathological Changes in Grossly Normal Caprine Mesenteric Lymph Nodes

Shailesh Kumar Patel1, Jigyasa Rana2, Rakesh Kumar1 and B.V. Rami Reddy1

1Division of Pathology, Indian Veterinary Research Institute, Izatnagar, Bareily-243122, Uttar Pradesh, India. 2Department of Veterinary Anatomy, C.V.A.Sc, G.B.P.U.A&T, Pantnagar-263145, Uttarakhand, India.

Received on 03 April 2015 and accepted on 09 June 2015

 

ABSTRACT

Mesenteric lymph nodes (MLN) are good indicators of intestinal health of animals. Lesions of MLN are commonly associated with infectious and malignant diseases. Unsuspected altered MLN are frequently encountered during necropsy. The aim of this study was to document microscopic findings in grossly normal MLN collected from apparently healthy goats. Mesenteric lymph node samples of 40 apparently normal goats were collected from goat slaughter house, Bareilly. Based on microscopic examination, the lesions were classified into four categories, namely inflammatory changes, reactive hyperplasia, lymphoid depletion and necrosis. Microscopic examination showed that ten out of the 40 (25%) MLN had inflammatory changes in cortex as well as medulla, six (15%) had cortical and para-cortical lymphoid hyperplasia, three (7.5%) showed lymphoid depletion in the cortex and five (12.5%) lymph nodes had necrotic lesions in the cortical area. Sixteen out of the 40 (40%) MLN did not have any significant histological changes. The results of the study showed that 60% of grossly normal MLN had significant microscopic lesions indicating that incidental abnormal findings of MLN are common, reflecting more widespread inapparent infections in goats.

Keywords : Mesenteric lymph nodes, Goats, Histopathology, Inflammatory changes, Reactive hyperplasia.