Novel series of 1-substituted phenyl-3-substituted phenyl-4-(o-carboxyphenyl) formazans (3a-3n) were synthesized by coupling aryl diazonium salts of various aromatic substituted amines with N-o-carboxyphenyl-2-substituted phenyl azomethines (2a-2f).
The later were prepared by condensation of anthranilic acid with various substituted aldehydes. The structures of all these compounds were established on the basis of elemental analysis, IR and ¹HNMR and mass spectral data. All the synthesized compounds have been screened for their antimicrobial activity against gram-positive, gram-negative and fungal pathogens. The synthesized compounds were found to have significant effect against the tested organisms.