Biopurification Technology of volatile organic compounds (VOCs) has the advantages of mild reaction conditions, low operating costs, less pollution. The paper reviews the current study on the packing characteristics, and long-running biofilm blockage, and kinetic model, and microorganism domestication and cultivation of high efficient degradation bacteria, and safety evaluation in the research of domestic and foreign scholars. Through the above analysis, the paper puts forward the existing problems using biological purification technology and future development trends. The aim is to improve the removal ability of the equipment unit volume and resistance to impact load capacity, and to prolong the service life of equipment, in order to drive the biological treatment technology in the practical application and industrialization.