ISSN: 0973-7510

E-ISSN: 2581-690X

Review Article | Open Access
Jehad A. Aldali1 , Abdullah Abutheeb2, Abdullah Al-Fahd2, Meshal Alzakari2, Omar Almukhalafi2, Nasser Al-Tayar2, Abdullah Almeziny2 and Razique Anwer1
1Department of Pathology, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
2College of Medicine, Imam Mohammed Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
Article Number: 8169 | © The Author(s). 2023
J Pure Appl Microbiol. 2023;17(2):641-649. https://doi.org/10.22207/JPAM.17.2.21
Received: 17 October 2022 | Accepted: 25 March 2023 | Published online: 04 May 2023
Issue online: June 2023
Abstract

In order to fight the coronavirus disease 2019 (COVID-19) pandemic, the AstraZeneca vaccine was introduced in the Saudi Arabian vaccination campaign. AstraZeneca was rapidly developed, and side effects have been reported following vaccination. This review aims to evaluate the adverse side-effects of the AstraZeneca vaccine within the Saudi population. A literature search of the national and international databases PubMed, Scopus, Google Scholar, Embase databases, and Cochrane Library using the search terms “Covid-19 vaccine”, “AstraZeneca post-vaccination,” and “Covid-19 vaccine Saudi Arabia” in combination with the terms “side effects,” “adverse effects,” and “Covid-19 AstraZeneca” was performed. Articles published before 12 January 2022 were eligible for screening. A total of seven articles met the inclusion criteria, totaling 4838 participants. The most common side effects were fever and either pain or redness at the site of the injection. Furthermore, systemic reactions to AstraZeneca accounted for approximately 80% of adverse effects following vaccination. In sum, AstraZeneca appears to have mild to moderate side effects.

Keywords

COVID-19, Vaccine, Side Effects, AstraZeneca

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© The Author(s) 2023. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.