ISSN: 0973-7510
E-ISSN: 2581-690X
The purpose of this research is esearching the the impact of ROCK caffeic acid phenethylester Y-27362 on cell growth and migration of esophageal cancer EC9706 and discussing the possible mechanisms. The main research method of this paper is culturing human esophageal cancer canopy EC9706 in vitro, adding 20umol/LY-27632 liquid (experiment group) and isometric PBS(control group) to culture for one hour, adopting cell counting, MTT experiment to test cell growth situation, using Transwell experiment to observe cell migration situation, employing Westem blot to detect the expression level of Cav-1,and making comparison of two groups. Finally it contrastively analyzes the results. The conclusion is that Rock caffeic acid phenethylester Y-27362 can restrict cell growth and migration of esophageal cancer EC9706, which provides a new idea and direction for curing esophageal cancer.
Esophageal cancer; preparation Y-27632, EC9706 cell
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